Interstitial lung disease primary Sjögren’s syndrome pulmonary fibrosis secondary Sjögren’s syndrome.This ship's prefix "MSC" indicates the owner, Mediterranean Shipping Company.Ī ship prefix is a combination of letters, usually, abbreviations, used in front of the name of a civilian or naval ship that has historically served numerous purposes, such as identifying the vessel's mode of propulsion, purpose, or ownership/nationality. sSS-ILD patients showed worse laboratory results and pulmonary function.KEY MESSAGEOlder age, male sex, female sex at menopause, Raynaud's phenomenon, low albumin levels and respiratory symptoms are risk factors associated with SS-ILD.SS-ILD patients show higher counts of platelets and less purpura.sSS-ILD patients have worse laboratory results and pulmonary function. NSIP is important HRCT feature of SS-ILD. Older age, male sex, female sex at menopause, Raynaud's phenomenon, low albumin levels and respiratory symptoms are risk factors associated with SS-ILD. ILD is a common pulmonary involvement in both pSS patients and sSS patients. 003), low levels of complement 3 (C3) ( p =. 013), a higher level of erythrocyte sedimentation rate (ESR) ( p =.
Compared with pSS patients with ILD (pSS-ILD) patients, sSS patients with ILD (sSS-ILD) patients had a higher incidence of proteinuria ( p <. NSIP (56.3%) was the most frequent HRCT pattern. The three most frequent high-resolution CT (HRCT) findings of SS-ILD were irregular linear opacities (42.7%), grid shadows (30.7%) and pleural thickening (28.5%). The SS-ILD group showed higher counts of platelets ( p <. Factors associated with SS-ILD were older age ( p <. No significant difference was found between the pSS and sSS groups concerning the incidence of ILD ( p =. Additionally, 316 (43.0%) were diagnosed with SS-ILD. Of the 735 SS patients enrolled in this study, 563 (76.6%) were diagnosed with pSS, 172 (23.4%) were diagnosed with sSS. Clinical manifestations, medical history, biological results and imaging data were collected. The medical records of hospitalized patients diagnosed with SS at the Second Xiangya Hospital of Central South University from January 2010 to May 2020 were retrospectively reviewed. This study aimed to elucidate both primary and secondary SS-associated ILD (SS-ILD) based on a large cohort. Most studies on primary SS (pSS) with ILD are limited in sample size, and studies on secondary SS (sSS) with ILD are rare. Interstitial lung disease (ILD) is a serious complication in patients with Sjögren's syndrome (SS).
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